Step 1: When hovering over an image, add a shadow to it.

Step 2: When mouse leaves image, remove the shadow.

Step 3: When clicking an image, replace Bill Murray with this picture: http://placecage.com/c/100/100, and change the opacity to all other images to 50%.

Step 4: Fix the hover rules so when you leave an image, all images reset to initial settings.

Answer

Edit in JS Bin